The 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to YWHAB. This antibody recognizes Human, Mouse, Rat, and Yeast/Fungi antigen. The 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon Antibody has been validated for the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2